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54th ERA-EDTA Congress

 

3rd-6th June 2017 Madrid
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Discussion forum - 54th ERA-EDTA Congress
    Topic - Dialysis - techniques & adequacy II

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Poster: 535
Visits: 8
Title: DOUBLE FILTRATION PLASMAPHERESIS IN THE SYMPTOMATIC HYPERVISCOSITY RELATED TO WALDENSTROMS MACROGLOBULINEMIA
Authors: Claudia Altobelli , Claudia Altobelli, Margherita Perrotta, Danilo Di Matteo, Antonello Sica, Salvatore Guastafierro, Giovambattista Capasso, Pietro Anastasio
Centre: University of Campania Luigi Vanvitelli

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DOUBLE FILTRATION PLASMAPHERESIS IN THE SYMPTOMATIC HYPERVISCOSITY RELATED TO WALDENSTROMS MACROGLOBULINEMIA

Claudia Altobelli
Thread initiator
Subspeciality
Reg: 5/17/2017 4:38:00 PM

Comment# 1

Hyperviscosity syndrome (HVS) in Waldenstroms macroglobulinemia (WM) is a rare life-threatening complication due to increased plasma viscosity, typically associated with monoclonal IgM. Guidelines of the American Society for Apheresis (ASFA 2016) recommends Plasmapheresis as first-line therapy in the symptomatic HVS and the prophylaxis for Rituximab with grade of evidence 1B and 1C, respectively. We used Double Filtration Plasmapheresis (DFPP) as semi-ive plasmapheresis technique to treat HVS in WM, because it is safer than plasma-exchange (not ive). A problem of DFPP is the loss of useful substances like fibrinogen; infact an important loss of fibrinogen increased hemorragic risk. In this study, we evaluated the percentage of reduction of immunoglobulins and the more significant factor involved in the reduction of fibrinogen.

Comment added on 5/17/2017 4:38:00 PM 
     
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Most viewed poster for this congress
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Title: IMPACT OF HEPARIN DOSES ON PATIENT TREATMENT OUTCOMES
Authors: Joao Fazendeiro Matos , R Peralta1, C Felix1, H Carvalho2, B Pinto1, P Ponce1, 1Fresenius Medical Care, NephroCare Portugal, Lisboa, PORTUGAL, 2Instituto Universitário de Lisboa (ISCTE-IUL), Centro de Investigaão e Estudos de Sociologia (CIES-IUL), Lisboa, PORTUGAL.
Centre: Fresenius Medical Care, NephroCare Portugal, Lisboa, PORTUGAL


 




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